In today’s fast-evolving aesthetic landscape, there’s a noticeable shift happening in treatment goals and patient expectations. Gone are the days of overfilled cheeks, frozen expressions, and immediately knowing who has had “work” done. Today’s patients are looking for something different – undetectable treatments. They want to look like themselves, just more refreshed, more radiant, more confident.
This demand for natural-looking results is more than a passing trend; it’s redefining what success in aesthetic medicine looks like. At the heart of this evolution is a growing focus on skin regeneration, an approach that works with the body rather than against it, leveraging its own biological processes to heal, strengthen, and regenerate.
Let’s dive into the data, the science, and the exciting new technology, including Glo₂Facial by Geneo, that’s powering the future of aesthetic medicine.

The Demand for Natural Enhancement
According to Merz Aesthetics’ Global Pillars of Confidence Study, which surveyed over 15,000 adults in 13 countries, a staggering 79% of consumers prefer treatments that enhance their natural features rather than alter their appearance. In the U.S., that number is even higher among Millennials and Gen X — groups that make up the core of today's med spa clientele.
Even more telling, nearly half of respondents (49%) expressed concern about getting results that look unnatural. This marks a profound shift in consumer behavior: today’s patients are both more educated and more intentional than ever. They’re not just looking for surface-level results — they’re seeking longevity, authenticity, and confidence.
Natural looking results are also one of the biggest deciding factors when a patient is choosing a practice, listed as the second most important factor after reputation and before cost, recommendations, location, ease of booking, and more.
What does this mean for your treatment room?
It means there might be a gap in your menu for treatments that enhance a natural look. Or a gap to build skin integrity earlier. When was the last time you evaluated your menu for treatments that focused on skin regeneration?
This global desire for natural results is pushing the entire aesthetics industry to think differently. It’s no longer about being reactive and chasing youth but taking preventative measures and proactively building the skin’s integrity. Patients want to preserve health, boost radiance, and slow aging in a way that feels holistic, not artificial. Patients will still seek fillers and neuromodulators, but possibly more in terms of facial balancing. And you need to offer them options that enhance the skin’s health in between injections, lasers, or peels to maintain and prep the surface.
Treatments like Glo₂Facial that work with the body using Oxfoliation™️ fill this gap as the oxygenation process encourages skin cell turnover. Our RF Pro modality hits a layer deeper at the dermis, encouraging the building of collagen and elastin bonds. And we all know the long-term impact of strong, healthy collagen for the appearance of youthful skin.
Lines and Wrinkles: Still the #1 Concern — But the Solutions Are Changing
While treatment goals have evolved, some concerns remain consistent. Year after year, lines and wrinkles top the list of aesthetic concerns. According to the American Society for Dermatologic Surgery (ASDS), 79% of patients report wrinkles as a primary focus — and this stat has held steady for over a decade.
What’s changing is how those lines are addressed. While neurotoxins and fillers still play a role, today’s patients are increasingly seeking preventative and regenerative options. They want treatments that support long-term skin quality, and noninvasive options.
This is where energy-based devices — and Glo₂Facial in particular — shine. Unlike injectables that target movement or volume, regenerative treatments stimulate collagen production, improve skin barrier function, and enhance dermal thickness from the inside out.
Glo₂Facial's use of radio frequency with RF Pro directly stimulates collagen and elastin, softening fine lines over time. The results appear immediately and continuously improve supporting the look and feel of healthy, youthful skin without freezing expression or changing facial structure. Again, we use the body’s own natural process for big impact. This noninvasive treatment also offers patients an alternative option that may not be ready or need a break from injections.
Aesthetic Fatigue and the Rise of “Skin Minimalism”
The concept of “aesthetic fatigue” — or the burnout from overcorrected, overdone treatments — is fueling the rise of a new movement: skin minimalism.
Patients are paring down their skincare routines, simplifying their aesthetic approach, and focusing on treatments that offer real skin health benefits. As NewBeauty reports in their 2024 Future of Beauty issue, noninvasive skin-boosting technologies are surging in popularity, particularly among professionals in their 30s and 40s who are beginning to think long-term about aging.
Consumers now understand that the best results come from healthy skin, not just wrinkle reduction. They’re gravitating toward treatments that restore skin integrity, protect the barrier, and improve texture, tone, and hydration.
Glo₂Facial delivers on this perfectly. With Oxfoliation™ — a proprietary combination of exfoliation and oxygenation — it encourages microcirculation and promotes a healthier skin barrier. Patients leave glowing, not because of a heavy peel or mask, but because their skin is functioning better.
The Power of Regenerative Technology
Glo₂Facial is more than a facial. It’s a high-performance, next-generation skin regeneration treatment. What makes it unique is its multi modality technology — a strategic combination of four powerful components that work synergistically to treat skin concerns from multiple angles:
RF Pro: Gently heats the dermis to trigger collagen and elastin production, visibly firming and lifting over time.
Oxfoliation™: A proprietary process that stimulates oxygenation at the skin’s surface while removing dead skin cells and increasing cell turnover.
Ultrasound: Delivers active ingredients deeper into the skin, maximizing absorption and impact.
Detox: Reduces puffiness, promotes detoxification, and enhances circulation for an instant glow.
Each of these technologies on their own offers value — but together, they deliver next-level skin transformation. The treatment respects the skin’s natural processes, creating improvement from within rather than simply “layering on” results.
No Downtime, No Pain: The New Standard of Care
Another driving factor in the popularity of regenerative treatments? Convenience.
In a world where time is the ultimate luxury, today’s aesthetic patient expects minimal disruption. As reported by NewBeauty, over 60% of med spa patients now prioritize “no downtime” as their top deciding factor when choosing treatments.
That’s why Glo₂Facial has such broad appeal — it offers visible improvement with no recovery period. Patients can receive a treatment over lunch and return to work or social activities immediately. There’s no flaking, no redness, no need to “hide out” for a few days.
How often are your patients seeking relaxation in conjunction with their corrective treatments? Do you have anything on your menu that does both? There is a trend towards “bespoke” facial treatments where patients want a full experience with the mix of technology and relaxation. They trust providers that seamlessly integrate the two.
Skin Health as the New Anti-Aging
There’s a growing realization in aesthetic medicine that true youthfulness isn’t about erasing every wrinkle — it’s about maintaining vibrancy, texture, tone, and clarity. Patients now understand that aging is a multifaceted process that impacts every layer of the skin.
Regenerative treatments like Glo₂Facial address aging more holistically by:
Restoring hydration and barrier health
Stimulating collagen production at the dermal level
Supporting detox and nutrient infusion
Improving texture, pore size, and radiance
This layered approach promotes the kind of skin that doesn’t just look good temporarily — it gets stronger over time. That’s the future of anti-aging: prevention and regeneration, not erasure.
Why Glo₂Facial Is Leading the Regenerative Revolution
While many devices and brands claim to support regeneration, few deliver on all the major pillars patients care about:
Natural-looking results
No pain, no downtime
Visible improvement in lines, texture, and radiance
Technology that supports long-term skin health
Glo₂Facial hits all of these — and adds an emotional benefit as well. Patients report not just better skin, but increased confidence, relaxation, and a renewed relationship with their appearance. Regular facials mean patients are taking care of their skin – which Merz reports is 82% of people’s main outcome after aesthetic treatments. 59% of patients see aesthetic treatments as regular beauty maintenance in comparison to life transitions or special events at 33% and 31% respectively. Glo₂Facial is that perfect intersection of clinically backed results patients need with a luxurious experience they want.
Plus, providers love it. With minimal consumables, simple protocols, and strong ROI, it’s an easy addition to any practice that wants to expand into results-driven skin health treatments.

The Skin Renaissance Has Begun
As we move into a new era of aesthetics, the focus is shifting from “how do I fix my face?” to “how do I support my skin?” It’s no longer about one-time transformations. It’s about long-term regeneration. What evidence are you seeing in your practice to support this?
The statistics from Merz Aesthetics and NewBeauty are clear: patients want subtle enhancement, smart technology, and treatments that leave them looking like the best version of themselves.
Are you ready to offer your patients the future of skin regeneration?
Contact our team or schedule a consultation to see how Glo₂Facial can transform your practice — and your patients’ skin — from the inside out.